文章摘要
.风湿骨痛药酒药槌外治法对兔退变腰椎间盘内磷脂酶A2活性的影响[J].,2011,13(3):.
风湿骨痛药酒药槌外治法对兔退变腰椎间盘内磷脂酶A2活性的影响
The effect of external treatment of medicated mallet of Fengshi Gutong Herb Liquor on phospholipase A2 activity in the degenerative intervertebral disc in rabbit model
  
DOI:
中文关键词: 腰椎间盘  椎间盘源性下腰痛  风湿骨痛药酒药槌外治法  磷脂酶A2  
英文关键词: Lumbar intervertebral disc  Discogenic low back pain  External treatment of Gutong Herb Liquor mallet  PLA2  
基金项目:湖北省教育厅重点科研项目(Q20091607)
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中文摘要:
      目的观察风湿骨痛药酒药槌对兔退变椎间盘内磷脂酶A2(PLA2)活性的影响,探讨其防治椎间盘源性下腰痛的机理。方法采用在X光机透视定位下经皮穿刺破坏椎间盘的造模方法,将21只实验兔随机分为3组:风湿骨痛药酒药槌外治法治疗组、药物治疗组和模型对照组。造模8周后开始治疗3,周后手术取L4-5椎间盘进行PLA2活性检测。结果与模型组比较,两治疗组PLA2活性明显降低(P<0.01)。外治法组与药物治疗组比较,PLA2活性无明显差异(P>0.05)。结论风湿骨痛药酒药槌外治法可降低椎间盘内PLA2活性,这可能是其防治椎间盘源性下腰痛的机制之一。
英文摘要:
      Objective To study the effect of external treatment of medicated mallet of Fengshi Gutong Herb Liquor on phospholipase A2 activity in the degenerative intervertebral disc in rabbit model and exploring its mechanism of treatment and prevention on discogenic low back pain.Methods 21 rabbits,after modeled by injuring the intervertebral disc percutaneously under X-ray,were randomly divided into 3 groups: mallet of Fengshi Gutong Herb Liquor group,medicine treatment group,model control group.Treatment was given ...
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